Milestones in Science: Celebrating 50 Years of Discovery at Rice

Living a Fluorine Future
Rice chemist John Margrave revolutionized fluorine chemistry with his discovery of CFX, a durable, heat-resistant compound used worldwide — from NASA to surgical gloves. His research advanced our understanding of reactive fluorine intermediates and enabled fluorination of fullerenes and nanotubes, expanding materials science. Margrave’s work established efficient synthesis methods and practical applications that remain foundational in fluorine chemistry today.
Learn how it happenedFLUORINE FOR MEDICINE, SUSTAINABILITY AND MATERIALS
Margrave’s trailblazing work set the stage for fluorine’s many possibilities. Today, Rice researchers are applying fluorine in transformative ways — from removing contaminants from water to developing next-generation medicines and materials. Read on for some of their remarkable stories.